Optical coherence tomography for the quantitative study of cerebrovascular physiology.

نویسندگان

  • Vivek J Srinivasan
  • Dmitriy N Atochin
  • Harsha Radhakrishnan
  • James Y Jiang
  • Svetlana Ruvinskaya
  • Weicheng Wu
  • Scott Barry
  • Alex E Cable
  • Cenk Ayata
  • Paul L Huang
  • David A Boas
چکیده

Doppler optical coherence tomography (DOCT) and OCT angiography are novel methods to investigate cerebrovascular physiology. In the rodent cortex, DOCT flow displays features characteristic of cerebral blood flow, including conservation along nonbranching vascular segments and at branch points. Moreover, DOCT flow values correlate with hydrogen clearance flow values when both are measured simultaneously. These data validate DOCT as a noninvasive quantitative method to measure tissue perfusion over a physiologic range.

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عنوان ژورنال:
  • Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

دوره 31 6  شماره 

صفحات  -

تاریخ انتشار 2011